CREATINE Tabs 100tabs
CREATINE ETHYL ESTER
Basic functions:
Energy, Strength, Recovery, Muscle Growth
Absorbed Better Than Regular Creatine Monohydrate!
What is Creatine Ethyl Ester and where does it come from?
Creatine Ethyl Ester HCL (CEE) is creatine monohydrate with an ester attached. Esters are organic compounds that are formed by esterification - the reaction of carboxylic acid and alcohols.
Creatine ethyl ester is a substance sold as an aid for athletic performance and for muscle development in bodybuilding. It is an ethyl ester derivative of creatine, from which it is made. In the body, CEE is converted back into creatine. The ethyl ester is said to have a much better absorption rate and a longer half-life in the body than regular creatine monohydrate, because it is slightly more lipophilic.
What does it do and what scientific studies give evidence to support this?
Regular creatine monohydrate has been shown effective at increasing lean muscle mass, muscle strengthand athletic performance.
However, regular creatine monohydrate is absorbed poorly by the body - and its effectiveness is dependant upon the cells ability to absorb it. The poor absorption rate of regular creatine monohydrate requires the creatine user to ingest large dosages of creatine to achieve the desired effect.
Because creatine draws water to the cell, and because most ingested creatine monohydrate is not absorbed, unabsorbed creatine will sit outside of the target cell with the water, and this will result in the "creatine bloat."
Long-term clinical studies have proven that creatine monohydrate is safe for use by persons free of medical complication, but why would you want to ingest more creatine monohydrate than you have to simply because your creatine is inefficient?
Creatine ethyl ester is creatine monohydrate with an ester attached. The attachment of an ester is significant, because esters are found in the fat tissue of animals. But, why is this important? What role does this have in the absorption of creatine?
All substances that you put into your body will affect its operation. There are three ways that substances can affect a cells operation. They are:
- Ligand binding to protein receptor sites.
- Secondary messenger / metabotropic systems
- Passive permeation of the cell wall via lipids
When a substance enters the body and affects the bodies operation, it is known as a ligand. The soma and dendrites of the cell have protein receptor sites to which ligands can bind. The process of a ligand binding with a receptor site is akin to a lock and key: only keys of a certain shape work with certain locks. When they work and cause the cells stimulation they are called agonists. When they block the cell from functioning they are called antagonists.
When a ligand binds with the receptor site of a target cell, the cell, in the simplest of cases, changes its shape, opens up its ion channels and changes its function. In so-called "secondary messenger" or metabotropic cells, the ligand binds with the receptor site and an internal protein known as a g-protein is released. This released protein then binds to an internal site inside of the cell, and then the cell changes its behavior by opening its ion channels. Cells that operate in this way are known as metabotropic cells because their operation requires metabolic energy.
Passive permeation is a process that describes the diffusion of a substance across a cell membrane through the use of lipids as transport mechanisms. Because no "work" is being done by the cell in this model, this model is called passive permeation.
Creatine monohydrate utilizes lipids to permeate the cell wall and enter the cell. Because of this, the esterification of creatine, and the presence of esters in animal fat tissue, becomes significant.
Creatine monohydrate is semi-lipopholic. This means that it inefficiently uses fat as a transport mechanism. The esterification of substances will increase their lipopholic abilities, and thus esterified creatine will use fat more efficiently to permeate the cell wall and exert its effects upon cellular function than its unesterified creatine monohydrate counterpart.
This means, simply, that not only will dosage requirements be lower, but the absorption of esterified creatine will be increased and the infamous "creatine bloat" will be eliminated!
Creatine Ethyl Ester can benefit persons of all ages, as it displays the same benefits as regular creatine monohydrate.
Much controversy has been generated over creatine ethyl ester. Companies and individuals with a financial interest in promoting creatine monohydrate products have attempted to discredit creatine ethyl ester. Some companies have even gone so far as to commission laboratory reports that show that creatine ethyl ester is not real.
The one report that states that creatine ethyl ester is not real was commissioned by an industry company with an interest in discrediting creatine ethyl ester. The two certificates of analysis included show that CEE is real and was done on raw source product and conducted by people with no financial interest in the promotion of creatine ethyl ester.
The key ingredients in Ethyl Creatine Tabs are: 100% Creatine Ethyl Esther
Directions: Take 2 tablets 30 minutes before exercise/weight training.
Ingredients: Each 400mg Tablet contains 100% Ethyl Creatine. Does not convert to Creatinine in the gut and does not retain fluid under the skin.
Warning:
This product is a sports supplement. Not to be used as the sole source of nutrition. Not suitable for children under 16. Not suitable for pregnant women.
